San Francisco 49ers 2025 Schedule. After another disappointing loss in the super bowl, the san francisco 49ers are ready to enter the 2025 season as potential favorites to bring home the franchise's sixth world. Faithful, we have reached the midway point of the 2025 nfl season.

If you want to talk about wholesale turnaround, this is a good place to start. San francisco will face each of their 2023 postseason opponents in the 2025 regular season [green bay (week 12), detroit (week 17) and kansas city (week 7)].